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WormBase Tree Display for Gene: WBGene00000498

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Name Class

WBGene00000498EvidenceCGC_data_submission
SMapS_parentSequenceY39H10A
IdentityVersion1
NameCGC_namechk-1Person_evidenceWBPerson1551
Sequence_nameY39H10A.7
Molecular_nameY39H10A.7a
Y39H10A.7a.1
CE26076
Y39H10A.7b
CE33867
Y39H10A.7b.1
Other_nameY39H10A.aCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y39H10A.7Accession_evidenceNDBBX284605
Public_namechk-1
DB_infoDatabase (14)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:21WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classchk
Allele (45)
StrainWBStrain00034800
WBStrain00034803
RNASeq_FPKM (74)
GO_annotation (23)
Contained_in_operonCEOP5515
Ortholog (57)
Paralog (30)
Structured_descriptionConcise_descriptionchk-1 encodes a CHK1-like serine threonin protein kinase that affects fertility.Paper_evidenceWBPaper00005039
Curator_confirmedWBPerson48
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable protein serine/threonine kinase activity. Involved in embryo development and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Expressed in germ line. Human ortholog(s) of this gene implicated in pancreatic cancer. Is an ortholog of human CHEK1 (checkpoint kinase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:1793Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1925)
EFO:MONDO:0014769Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1925)
Molecular_infoCorresponding_CDSY39H10A.7a
Y39H10A.7b
Corresponding_transcriptY39H10A.7a.1
Y39H10A.7b.1
Other_sequence (15)
Associated_featureWBsf652545
WBsf668844
WBsf668845
WBsf668846
WBsf999681
WBsf999682
WBsf1019419
WBsf233520
WBsf233521
WBsf233522
Experimental_infoRNAi_result (53)
Expr_patternExpr3082
Expr4894
Expr9219
Expr1011525
Expr1030294
Expr1159784
Expr1200236
Expr2009991
Expr2028232
Drives_constructWBCnstr00037496
WBCnstr00038171
Construct_productWBCnstr00037496
WBCnstr00038171
Microarray_results (26)
Expression_cluster (145)
Interaction (138)
Map_infoMapVPosition-8.01265Error0.002467
PositivePositive_cloneY39H10AInferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5377
Pseudo_map_position
Reference (51)
RemarkSequence connection from [Boulton S, Vidal M]
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene