WormBase Tree Display for Gene: WBGene00000292

WBGene00000292 SMap: S_parent: Sequence: D2024
  Identity: Version: 1
    Name: CGC_name: cap-1 Person_evidence: WBPerson1562
      Sequence_name: D2024.6
      Molecular_name: D2024.6
        D2024.6.1
        CE04295
      Other_name: CAPZ/A
        CELE_D2024.6 Accession_evidence: NDB BX284604
      Public_name: cap-1
    DB_info: Database: AceView gene 4H994
        WormQTL gene WBGene00000292
        WormFlux gene WBGene00000292
        NDB locus_tag CELE_D2024.6
        Panther gene CAEEL|WormBase=WBGene00000292|UniProtKB=P34685
          family PTHR10653
        NCBI gene 177497
        RefSeq protein NM_068744.6
        SwissProt UniProtAcc P34685
        TREEFAM TREEFAM_ID TF314822
        UniProt_GCRP UniProtAcc P34685
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cap
    Allele (20)
    Legacy_information: [C.elegansII] NMK. Encodes homolog of actin capping protein, alpha subunit.Functional in yeast. [Waddle et al. 1993]
    Strain: WBStrain00028916
      WBStrain00055410
    RNASeq_FPKM (74)
    GO_annotation (11)
    Contained_in_operon: CEOP4216
    Ortholog (45)
    Structured_description: Concise_description: cap-1 encodes an F-actin capping protein alpha subunit that affects fertility; likely expressed in touch receptor neurons. Paper_evidence: WBPaper00001839
            WBPaper00004651
            WBPaper00005356
          Curator_confirmed: WBPerson48
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable actin filament binding activity. Predicted to be involved in actin cytoskeleton organization and barbed-end actin filament capping. Part of dynactin complex. Human ortholog(s) of this gene implicated in male infertility. Is an ortholog of human CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1) and CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:12336 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:24205)
  Molecular_info: Corresponding_CDS: D2024.6
    Corresponding_transcript: D2024.6.1
    Other_sequence (48)
    Associated_feature: WBsf651895
      WBsf668004
      WBsf230233
      WBsf230234
  Experimental_info: RNAi_result: WBRNAi00088764 Inferred_automatically: RNAi_primary
      WBRNAi00008578 Inferred_automatically: RNAi_primary
      WBRNAi00090793 Inferred_automatically: RNAi_primary
      WBRNAi00007972 Inferred_automatically: RNAi_primary
      WBRNAi00043464 Inferred_automatically: RNAi_primary
      WBRNAi00088657 Inferred_automatically: RNAi_primary
      WBRNAi00091225 Inferred_automatically: RNAi_primary
      WBRNAi00085703 Inferred_automatically: RNAi_primary
      WBRNAi00091224 Inferred_automatically: RNAi_primary
      WBRNAi00001944 Inferred_automatically: RNAi_primary
    Expr_pattern: Chronogram1048
      Expr5625
      Expr16434
      Expr1010907
      Expr1030189
      Expr1147458
      Expr2009715
      Expr2027954
    Drives_construct: WBCnstr00002987
      WBCnstr00009612
      WBCnstr00037600
    Construct_product: WBCnstr00037600
    Antibody: WBAntibody00001781
    Microarray_results (20)
    Expression_cluster (102)
    Interaction (119)
  Map_info: Map: IV Position: 3.30656 Error: 0.001843
    Positive: Positive_clone: BW#ZA
        D2024 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (18)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene