WormBase Tree Display for Gene: WBGene00000250

WBGene00000250 SMap: S_parent: Sequence: C50B8
  Identity: Version: 1
    Name: CGC_name: bir-2 Person_evidence: WBPerson250
      Sequence_name: C50B8.2
      Molecular_name: C50B8.2
        C50B8.2.1
        CE08882
      Other_name: CELE_C50B8.2 Accession_evidence: NDB BX284605
      Public_name: bir-2
    DB_info: Database: AceView gene 5O49
        WormQTL gene WBGene00000250
        WormFlux gene WBGene00000250
        NDB locus_tag CELE_C50B8.2
        Panther gene CAEEL|WormBase=WBGene00000250|UniProtKB=G5ECJ5
          family PTHR46771
        NCBI gene 179841
        RefSeq protein NM_073961.6
        SwissProt UniProtAcc G5ECJ5
        TREEFAM TREEFAM_ID TF316930
        UniProt_GCRP UniProtAcc G5ECJ5
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: bir
    Allele (20)
    Strain: WBStrain00051230
    RNASeq_FPKM (74)
    GO_annotation: 00011929
      00106041
      00106042
      00106043
    Ortholog (27)
    Paralog: WBGene00006712 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: The bir-2 gene encodes a protein with two BIR domains that may be involved in apoptosis. Paper_evidence: WBPaper00004589
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable metal ion binding activity. Acts upstream of or within with a positive effect on germ cell proliferation. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); endometrial hyperplasia; and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue. Is an ortholog of human BIRC2 (baculoviral IAP repeat containing 2); BIRC3 (baculoviral IAP repeat containing 3); and BIRC5 (baculoviral IAP repeat containing 5). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (21)
  Molecular_info: Corresponding_CDS: C50B8.2
    Corresponding_transcript: C50B8.2.1
    Other_sequence: Tcir_isotig12083
      FD516205.1
      Acan_isotig01172
      FD514190.1
      CSC00581_1
      FK670257.1
      CR00729
      Acan_isotig01170
      CRC01335_1
    Associated_feature: WBsf647466
      WBsf232793
  Experimental_info: RNAi_result: WBRNAi00097133 Inferred_automatically: RNAi_primary
      WBRNAi00001529 Inferred_automatically: RNAi_primary
      WBRNAi00012184 Inferred_automatically: RNAi_primary
      WBRNAi00082709 Inferred_automatically: RNAi_primary
      WBRNAi00114635 Inferred_automatically: RNAi_primary
      WBRNAi00008113 Inferred_automatically: RNAi_primary
      WBRNAi00042859 Inferred_automatically: RNAi_primary
      WBRNAi00063168 Inferred_automatically: RNAi_primary
      WBRNAi00027849 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1275
      Expr1010936
      Expr1030160
      Expr1146838
      Expr2009626
      Expr2027864
    Drives_construct: WBCnstr00037629
    Construct_product: WBCnstr00037629
    Microarray_results (18)
    Expression_cluster (136)
    Interaction (251)
  Map_info: Map: V Position: 5.46147 Error: 0.002065
    Positive: Positive_clone: C50B8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00003470
    WBPaper00005538
    WBPaper00005976
    WBPaper00023134
    WBPaper00023666
    WBPaper00034806
    WBPaper00038491
    WBPaper00055976
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene