WormBase Tree Display for Gene: WBGene00000236

WBGene00000236 SMap: S_parent: Sequence: F57B10
  Identity: Version: 1
    Name: CGC_name: bag-1 Person_evidence: WBPerson434
      Sequence_name: F57B10.11
      Molecular_name: F57B10.11
        F57B10.11.1
        CE11318
      Other_name: CELE_F57B10.11 Accession_evidence: NDB BX284601
      Public_name: bag-1
    DB_info: Database: AceView gene 1H140
        WormQTL gene WBGene00000236
        WormFlux gene WBGene00000236
        NDB locus_tag CELE_F57B10.11
        Panther gene CAEEL|WormBase=WBGene00000236|UniProtKB=O44739
          family PTHR12329
        NCBI gene 172373
        RefSeq protein NM_059492.8
        SwissProt UniProtAcc O44739
        TREEFAM TREEFAM_ID TF102011
        UniProt_GCRP UniProtAcc O44739
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:20 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: bag
    Allele (15)
    RNASeq_FPKM (74)
    GO_annotation (13)
    Contained_in_operon: CEOP1340
    Ortholog (31)
    Structured_description: Concise_description: A homolog of the human BAG-family of co-chaperone proteins, negatively regulates Hsp70 and affects cell stress and cell growth. Paper_evidence: WBPaper00003367
            WBPaper00018256
          Curator_confirmed: WBPerson324
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enables ATPase activator activity. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein stabilization. Predicted to be located in cytosol; membrane; and nucleus. Human ortholog(s) of this gene implicated in breast cancer and reproductive organ cancer (multiple). Is an ortholog of human BAG1 (BAG cochaperone 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:10283 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:937)
      DOID:2893 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:937)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:937)
      DOID:1380 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:937)
  Molecular_info: Corresponding_CDS: F57B10.11
    Corresponding_transcript: F57B10.11.1
    Other_sequence (11)
    Associated_feature: WBsf649246
      WBsf219607
  Experimental_info: RNAi_result: WBRNAi00062279 Inferred_automatically: RNAi_primary
      WBRNAi00076496 Inferred_automatically: RNAi_primary
      WBRNAi00027869 Inferred_automatically: RNAi_primary
      WBRNAi00003837 Inferred_automatically: RNAi_primary
      WBRNAi00106350 Inferred_automatically: RNAi_primary
      WBRNAi00048816 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1026192
      Expr1030150
      Expr1152572
      Expr2009527
      Expr2027764
    Drives_construct: WBCnstr00037640
    Construct_product: WBCnstr00037640
    Microarray_results (17)
    Expression_cluster (116)
    Interaction (52)
  Map_info: Map: I Position: 1.21339 Error: 0.000398
    Positive: Positive_clone: F57B10 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00003367
    WBPaper00005356
    WBPaper00018256
    WBPaper00023457
    WBPaper00038491
    WBPaper00040951
    WBPaper00045536
    WBPaper00055090
  Remark: Sequence connection from [Nollen E, Morimoto R]. krb 13/11/01
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene