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WormBase Tree Display for Gene: WBGene00000186

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Name Class

WBGene00000186SMapS_parentSequenceC01C7
IdentityVersion1
NameCGC_nameark-1Person_evidenceWBPerson625
Sequence_nameC01C7.1
Molecular_nameC01C7.1a
C01C7.1a.1
CE26967
C01C7.1b
CE43742
C01C7.1b.1
Other_namerok-1
CELE_C01C7.1Accession_evidenceNDBBX284604
Public_nameark-1
DB_infoDatabase (13)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classark
Allele (153)
Legacy_informationnegatively regulates vulval differentiation [PS]
[C.elegansII] sy187 : negatively regulates vulval differentiation;20C no phenotype alone, 25C some excess vulval differentiation; more in sli-1(sy243) background. [PS]
StrainWBStrain00027395
WBStrain00030839
WBStrain00030876
RNASeq_FPKM (74)
GO_annotation (28)
Ortholog (34)
Paralog (45)
Structured_descriptionConcise_descriptionark-1 encodes a homolog of the nonreceptor tyrosine kinase ACK which inhibits signalling through the EGF receptor homolog LET-23, both in (RAS-dependent) vulval development and in (RAS-independent) ovulation.Paper_evidenceWBPaper00004273
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable protein tyrosine kinase activity. Involved in embryo development; negative regulation of epidermal growth factor receptor signaling pathway; and negative regulation of vulval development.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC01C7.1a
C01C7.1b
Corresponding_CDS_historyC01C7.1:wp46
Corresponding_transcriptC01C7.1a.1
C01C7.1b.1
Other_sequence (41)
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00085936Inferred_automaticallyRNAi_primary
WBRNAi00085934Inferred_automaticallyRNAi_primary
WBRNAi00039297Inferred_automaticallyRNAi_primary
WBRNAi00085935Inferred_automaticallyRNAi_primary
WBRNAi00085932Inferred_automaticallyRNAi_primary
WBRNAi00085933Inferred_automaticallyRNAi_primary
WBRNAi00092169Inferred_automaticallyRNAi_primary
Expr_patternExpr1019576
Expr1030109
Expr1143415
Expr2009398
Expr2027634
Microarray_results (21)
Expression_cluster (117)
Interaction (72)
WBProcessWBbiopr:00000071
Map_infoMapIVPosition6.12267Error0.004541
PositivePositive_cloneC01C7Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Mapping_dataMulti_point4162
4444
5595
Pseudo_map_position
Reference (36)
Remarknear unc-31
on chromosome IV
rok-1 was merged into this gene by krb on advice of JAH 25/02/02
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene