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WormBase Tree Display for Gene: WBGene00000181

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Name Class

WBGene00000181SMapS_parentSequenceF01G4
IdentityVersion1
NameCGC_nameard-1
Sequence_nameF01G4.2
Molecular_nameF01G4.2a
F01G4.2a.1
CE03127
F01G4.2b
CE49748
F01G4.2b.1
Other_nameCELE_F01G4.2Accession_evidenceNDBBX284604
Public_nameard-1
DB_infoDatabaseAceViewgene4L897
WormQTLgeneWBGene00000181
WormFluxgeneWBGene00000181
NDBlocus_tagCELE_F01G4.2
PanthergeneCAEEL|WormBase=WBGene00000181|UniProtKB=Q19102
familyPTHR43658
NCBIgene178016
RefSeqproteinNM_001307064.3
NM_069682.8
TrEMBLUniProtAccQ19102
A0A061AD09
UniProt_GCRPUniProtAccQ19102
OMIMgene300256
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classard
Allele (29)
StrainWBStrain00049398
RNASeq_FPKM (74)
GO_annotation00000186
00000187
00000188
00000189
00000190
00000191
Contained_in_operonCEOP4412
Ortholog (44)
Paralog (38)
Structured_descriptionConcise_descriptionard-1 encodes a homolog of mammalian 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD) that is predicted to be mitochondrial.Paper_evidenceWBPaper00004424
WBPaper00012828
WBPaper00013599
WBPaper00013615
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable estradiol 17-beta-dehydrogenase [NAD(P)] activity. Predicted to be involved in androgen metabolic process; estrogen metabolic process; and fatty acid metabolic process. Predicted to be located in mitochondrion. Expressed in hypodermis. Human ortholog(s) of this gene implicated in Alzheimer's disease; osteosarcoma; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Is an ortholog of human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4800)
DOID:3347Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4800)
DOID:0060810Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4800)
DOID:0050771Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4800)
Molecular_infoCorresponding_CDSF01G4.2a
F01G4.2b
Corresponding_transcriptF01G4.2a.1
F01G4.2b.1
Other_sequence (74)
Associated_featureWBsf997771
WBsf997772
WBsf1018176
WBsf229103
WBsf229104
Experimental_infoRNAi_resultWBRNAi00025001Inferred_automaticallyRNAi_primary
WBRNAi00027256Inferred_automaticallyRNAi_primary
WBRNAi00043779Inferred_automaticallyRNAi_primary
WBRNAi00076269Inferred_automaticallyRNAi_primary
WBRNAi00012757Inferred_automaticallyRNAi_primary
WBRNAi00102583Inferred_automaticallyRNAi_primary
WBRNAi00030558Inferred_automaticallyRNAi_primary
WBRNAi00102692Inferred_automaticallyRNAi_primary
WBRNAi00102683Inferred_automaticallyRNAi_primary
WBRNAi00102674Inferred_automaticallyRNAi_primary
Expr_patternExpr8141
Expr12157
Expr1024424
Expr1030105
Expr1147756
Expr2009389
Expr2027625
Drives_constructWBCnstr00013141
WBCnstr00020295
WBCnstr00037681
Construct_productWBCnstr00037681
Microarray_results (21)
Expression_cluster (112)
Interaction (60)
Map_infoMapIVPosition4.90778
PositivePositive_cloneF01G4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00026640
WBPaper00026800
WBPaper00028352
WBPaper00031915
WBPaper00038491
WBPaper00041771
WBPaper00042257
WBPaper00055090
WBPaper00062444
WBPaper00062625
RemarkThe name sad was previously used for this Short-chain Alcohol Dehydrogenase ERAB family by Carl Johnson.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene