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WormBase Tree Display for Gene: WBGene00000107

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Name Class

WBGene00000107SMapS_parentSequenceF54D8
IdentityVersion1
NameCGC_namealh-1Person_evidenceWBPerson651
Sequence_nameF54D8.3
Molecular_nameF54D8.3a
F54D8.3a.1
CE29809
F54D8.3b
CE32434
F54D8.3b.1
F54D8.3b.2
Other_nameCELE_F54D8.3Accession_evidenceNDBBX284603
Public_namealh-1
DB_infoDatabaseAceViewgene3G169
WormQTLgeneWBGene00000107
WormFluxgeneWBGene00000107
NDBlocus_tagCELE_F54D8.3
PanthergeneCAEEL|WormBase=WBGene00000107|UniProtKB=Q20780
familyPTHR11699
NCBIgene175691
RefSeqproteinNM_001392085.1
NM_065680.8
TrEMBLUniProtAccQ8IG19
Q20780
UniProt_GCRPUniProtAccQ20780
OMIMgene603687
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:20WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classalh
Allele (38)
StrainWBStrain00001668
WBStrain00001202
WBStrain00001584
WBStrain00001669
WBStrain00003724
RNASeq_FPKM (74)
GO_annotation00069116
00069117
00106798
00106799
Ortholog (48)
Paralog (11)
Structured_descriptionConcise_descriptionalh-1 is orthologous to the human gene ALDEHYDE DEHYDROGENASE 2, MITOCHONDRIAL (ALDH2; OMIM:100650), in which a polymorphism can lead to acute ethanol intolerance.Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable aldehyde dehydrogenase (NAD+) activity. Used to study obesity. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); diabetes mellitus (multiple); and liver disease (multiple). Is an ortholog of human ALDH1B1 (aldehyde dehydrogenase 1 family member B1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoExperimental_modelDOID:9970Homo sapiensPaper_evidenceWBPaper00035962
Curator_confirmedWBPerson38202
Date_last_updated29 Jun 2018 00:00:00
Potential_model (16)
Models_disease_in_annotationWBDOannot00000567
Molecular_infoCorresponding_CDSF54D8.3a
F54D8.3b
Corresponding_transcriptF54D8.3a.1
F54D8.3b.1
F54D8.3b.2
Other_sequence (113)
Associated_featureWBsf645145
WBsf224855
WBsf224856
WBsf224857
WBsf224858
WBsf224859
WBsf224860
Experimental_infoRNAi_result (16)
Expr_pattern (11)
Drives_constructWBCnstr00002095
WBCnstr00002424
WBCnstr00004159
WBCnstr00004219
WBCnstr00037727
Construct_productWBCnstr00037727
Microarray_results (32)
Expression_cluster (187)
Interaction (169)
Map_infoMapIIIPosition-2.19982Error0.004626
PositivePositive_cloneF54D8Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
Reference (11)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene