WormBase Tree Display for Gene: WBGene00000063
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| WBGene00000063 | SMap | S_parent | Sequence | T04C12 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | act-1 | Person_evidence | WBPerson259 | |||||
| Sequence_name | T04C12.6 | ||||||||
| Molecular_name | T04C12.6 | ||||||||
| T04C12.6.1 | |||||||||
| CE13148 | |||||||||
| Other_name | CELE_T04C12.6 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | act-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:19 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | act | ||||||||
| Allele (13) | |||||||||
| Strain | WBStrain00033488 | ||||||||
| In_cluster | act-123 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (46) | |||||||||
| Paralog (11) | |||||||||
| Structured_description | Concise_description | act-1 encodes an actin isoform that is required for proper body wall muscle and pharyngeal muscle structures and the motility of animals; actins have highly similar amino acid sequences; ACT-1 is identical to ACT-3; act-1 functions redundantly with two other actin isoforms, act-2 and act-3, to control cytoplasmic microfilament function in the early embryo. | Paper_evidence | WBPaper00001178 | |||||
| WBPaper00014413 | |||||||||
| WBPaper00027028 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 29 Mar 2007 00:00:00 | ||||||||
| Automated_description | Predicted to be a structural constituent of cytoskeleton. Involved in cortical actin cytoskeleton organization; embryo development; and mitotic cytokinesis. Located in striated muscle thin filament. Expressed in body wall musculature and gonad. Human ortholog(s) of this gene implicated in several diseases, including Baraitser-Winter syndrome 1; Baraitser-Winter syndrome 2; and autosomal dominant nonsyndromic deafness 20. Is an ortholog of human ACTB (actin beta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:1588 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||
| DOID:0081113 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:144) | ||||||
| DOID:10881 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||||
| DOID:0081112 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:132) | ||||||
| DOID:0110550 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:144) | ||||||
| Molecular_info | Corresponding_CDS | T04C12.6 | |||||||
| Corresponding_transcript | T04C12.6.1 | ||||||||
| Other_sequence (456) | |||||||||
| Associated_feature | WBsf647226 | ||||||||
| WBsf647227 | |||||||||
| WBsf661678 | |||||||||
| WBsf661679 | |||||||||
| WBsf1001264 | |||||||||
| WBsf1001265 | |||||||||
| WBsf1020400 | |||||||||
| WBsf232452 | |||||||||
| WBsf232453 | |||||||||
| WBsf232454 | |||||||||
| Experimental_info | RNAi_result (55) | ||||||||
| Expr_pattern | Expr558 | ||||||||
| Expr2793 | |||||||||
| Expr4555 | |||||||||
| Expr9252 | |||||||||
| Expr1030024 | |||||||||
| Expr1156000 | |||||||||
| Expr2009221 | |||||||||
| Expr2027458 | |||||||||
| Drives_construct | WBCnstr00006031 | ||||||||
| WBCnstr00006032 | |||||||||
| WBCnstr00013852 | |||||||||
| WBCnstr00037760 | |||||||||
| Construct_product | WBCnstr00015675 | ||||||||
| WBCnstr00015678 | |||||||||
| WBCnstr00037760 | |||||||||
| WBCnstr00038658 | |||||||||
| Antibody | WBAntibody00001783 | ||||||||
| Microarray_results | SMD_T04C12.6 | ||||||||
| GPL19516_CGZ0033111 | |||||||||
| GPL19516_CGZ0033112 | |||||||||
| GPL19516_CGZ0033113 | |||||||||
| GPL19516_CGZ0033114 | |||||||||
| GPL21109_T04C12.6.1 | |||||||||
| GPL8304_CE_WBGene00000063_B | |||||||||
| GPL9450_T04C12.6 | |||||||||
| cea2.c.38095 | |||||||||
| Expression_cluster (171) | |||||||||
| Interaction (326) | |||||||||
| WBProcess | WBbiopr:00000096 | ||||||||
| Map_info | Map | V | Position | 2.94475 | Error | 0.000513 | |||
| Positive | Positive_clone | T04C12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (106) | |||||||||
| Remark | T04C12.4 changed to T04C12.6. email from JAH 0109 | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
