WormBase Tree Display for Gene: WBGene00000060
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| WBGene00000060 | SMap | S_parent | Sequence | F27B3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | acr-21 | Person_evidence | WBPerson1430 | |||||
| Sequence_name | F27B3.2 | ||||||||
| Molecular_name (12) | |||||||||
| Other_name | CELE_F27B3.2 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | acr-21 | ||||||||
| DB_info | Database | AceView | gene | 3H673 | |||||
| WormQTL | gene | WBGene00000060 | |||||||
| WormFlux | gene | WBGene00000060 | |||||||
| NDB | locus_tag | CELE_F27B3.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00000060|UniProtKB=A0A3P6P985 | |||||||
| family | PTHR18945 | ||||||||
| NCBI | gene | 185004 | |||||||
| RefSeq | protein | NM_001368433.3 | |||||||
| NM_001368431.3 | |||||||||
| NM_001368432.3 | |||||||||
| NM_001368430.2 | |||||||||
| TrEMBL | UniProtAcc | A0A3P6N6F5 | |||||||
| A0A3P6NP92 | |||||||||
| A0A3P6P985 | |||||||||
| A0A3P6MY71 | |||||||||
| UniProt_GCRP | UniProtAcc | A0A3P6P985 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:19 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | acr | ||||||||
| Allele (78) | |||||||||
| Strain | WBStrain00031950 | ||||||||
| WBStrain00035013 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (28) | |||||||||
| Ortholog (36) | |||||||||
| Paralog (100) | |||||||||
| Structured_description | Concise_description | acr-21 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR); ACR-21 is a highly divergent member of the 'ACR-16' class of nAChR subunits, which includes ACR-7, ACR-9, ACR-10, ACR-11, ACR-14, ACR-15, ACR-16, and ACR-19, and is most closely related to the alpha-7 subunits of vertebrate nAChRs. | Paper_evidence | WBPaper00005223 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in cholinergic neurons and ventral cord neurons. Human ortholog(s) of this gene implicated in lung small cell carcinoma. Is an ortholog of human CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:5409 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:14079) | ||||
| Molecular_info | Corresponding_CDS | F27B3.2a | |||||||
| F27B3.2b | |||||||||
| F27B3.2c | |||||||||
| F27B3.2d | |||||||||
| Corresponding_CDS_history | F27B3.2:wp88 | ||||||||
| F27B3.2:wp151 | |||||||||
| F27B3.2:wp268 | |||||||||
| Corresponding_transcript | F27B3.2a.1 | ||||||||
| F27B3.2b.1 | |||||||||
| F27B3.2c.1 | |||||||||
| F27B3.2d.1 | |||||||||
| Other_sequence | Dviv_isotig30124 | ||||||||
| PPC01161_1 | |||||||||
| MH01913 | |||||||||
| DIC00454_1 | |||||||||
| AS17838 | |||||||||
| JO468037.1 | |||||||||
| MHC00632_1 | |||||||||
| JI170678.1 | |||||||||
| ASC25431_1 | |||||||||
| PP02143 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00045713 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00013989 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031481 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr9872 | ||||||||
| Expr1023885 | |||||||||
| Expr1149625 | |||||||||
| Expr1200296 | |||||||||
| Expr2009188 | |||||||||
| Drives_construct | WBCnstr00009848 | ||||||||
| WBCnstr00037763 | |||||||||
| Construct_product | WBCnstr00037763 | ||||||||
| Microarray_results (17) | |||||||||
| Expression_cluster (82) | |||||||||
| Interaction | WBInteraction000261051 | ||||||||
| WBInteraction000330425 | |||||||||
| Map_info | Map | III | Position | -1.06307 | Error | 0.002736 | |||
| Positive | Positive_clone | F27B3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4987 | |||||||
| 4136 | |||||||||
| 4626 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (14) | |||||||||
| Remark | Sequence connection from [Mongan NP, Jones AK, Sattelle DB], [krb 020711] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
