WormBase Tree Display for Disease_model_annotation: WBDOannot00001172
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| WBDOannot00001172 | Disease_term | DOID:162 | |
|---|---|---|---|
| Disease_of_species | Homo sapiens | ||
| Modeled_by | Variation | WBVar00091704 | |
| Asserted_gene | WBGene00006618 | ||
| Association_type | is_implicated_in | ||
| Evidence_code | GO_code | IMP | |
| ECO_term | ECO:0007013 | ||
| Experimental_condition | Inducing_chemical | WBMol:00004322 | |
| Genetic_sex | hermaphrodite | ||
| Paper_evidence | WBPaper00061243 | ||
| Disease_model_description | Cells surviving crisis are often tumorigenic and their telomeres are maintained through the reactivation of telomerase; surviving cells occasionally activate a recombination-based mechanism called alternative lengthening of telomeres (ALT); stably maintained survivors can be generated in C. elegans and escape sterility by activating ALT. | ||
| Curator_confirmed | WBPerson324 | ||
| Date_last_updated | 02 May 2022 00:00:00 |
