WormBase Tree Display for Gene: RGD:621414
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RGD:621414 | Identity | Name | CGC_name | Kcnh2 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Public_name | Kcnh2 | |||||
DB_info | Database | RGD | id | 621414 | ||
AGR | cURI | RGD:621414 | ||||
EnsEMBL | ENSEMBL_geneID | ENSRNOG00000009872 | ||||
UniProt | UniProt_AC | O08962 | ||||
Species | Rattus norvegicus | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog | WBGene00006830 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
Inparanoid | ||||||
OrthoFinder | ||||||
OrthoInspector | ||||||
Panther | ||||||
PhylomeDB | ||||||
SonicParanoid | ||||||
Structured_description | Automated_description | Enables inward rectifier potassium channel activity and scaffold protein binding activity. Involved in potassium ion transport; regulation of membrane potential; and spinal cord development. Predicted to be located in several cellular components, including cell surface; nuclear envelope; and perinuclear region of cytoplasm. Predicted to be part of inward rectifier potassium channel complex. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol. | Inferred_automatically | AGR_import |