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WormBase Tree Display for Gene: RGD:621414

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Name Class

RGD:621414IdentityNameCGC_nameKcnh2Inferred_automaticallyAGR_import
Public_nameKcnh2
DB_infoDatabaseRGDid621414
AGRcURIRGD:621414
EnsEMBLENSEMBL_geneIDENSRNOG00000009872
UniProtUniProt_ACO08962
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00006830Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Inparanoid
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionEnables inward rectifier potassium channel activity and scaffold protein binding activity. Involved in potassium ion transport; regulation of membrane potential; and spinal cord development. Predicted to be located in several cellular components, including cell surface; nuclear envelope; and perinuclear region of cytoplasm. Predicted to be part of inward rectifier potassium channel complex. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.Inferred_automaticallyAGR_import