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WormBase Tree Display for Gene: RGD:62081

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Name Class

RGD:62081IdentityNameCGC_nameHes1Inferred_automaticallyAGR_import
Public_nameHes1
DB_infoDatabaseRGDid62081
AGRcURIRGD:62081
EnsEMBLENSEMBL_geneIDENSRNOG00000001720
UniProtUniProt_ACQ04666
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00003008Caenorhabditis elegansFrom_analysisInparanoid
OrthoInspector
SonicParanoid
Structured_descriptionAutomated_descriptionEnables several functions, including JUN kinase binding activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription corepressor binding activity. Involved in several processes, including cellular response to cytokine stimulus; regulation of gene expression; and regulation of gliogenesis. Located in nuclear matrix. Part of chromatin. Used to study chronic myeloid leukemia and epilepsy. Biomarker of acute kidney failure. Orthologous to human HES1 (hes family bHLH transcription factor 1); PARTICIPATES IN Notch signaling pathway; maturity-onset diabetes of the young pathway; Notch signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.Inferred_automaticallyAGR_import