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WormBase Tree Display for Gene: RGD:620639

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Name Class

RGD:620639IdentityNameCGC_nameSlc7a5Inferred_automaticallyAGR_import
Public_nameSlc7a5
DB_infoDatabaseRGDid620639
AGRcURIRGD:620639
EnsEMBLENSEMBL_geneIDENSRNOG00000018824
UniProtUniProt_ACQ63016
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00000002Caenorhabditis elegansFrom_analysisInparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
WBGene00000004Caenorhabditis elegansFrom_analysisInparanoid
OMA
OrthoFinder
OrthoInspector
Panther
SonicParanoid
WBGene00000003Caenorhabditis elegansFrom_analysisHieranoid
OMA
Panther
Structured_descriptionAutomated_descriptionEnables amino acid transmembrane transporter activity. Involved in several processes, including amino acid transport; cellular response to L-arginine; and liver regeneration. Located in basolateral plasma membrane and external side of apical plasma membrane. Used to study high grade glioma. Biomarker of hepatocellular carcinoma and transitional cell carcinoma. Human ortholog(s) of this gene implicated in cholangiocarcinoma; colon cancer; hepatocellular carcinoma; and lung squamous cell carcinoma. Orthologous to human SLC7A5 (solute carrier family 7 member 5); PARTICIPATES IN mTOR signaling pathway; amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.Inferred_automaticallyAGR_import