WormBase Tree Display for Gene: RGD:2475
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| RGD:2475 | Identity | Name | CGC_name | Cyp2e1 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Public_name | Cyp2e1 | |||||
| DB_info | Database | RGD | id | 2475 | ||
| AGR | cURI | RGD:2475 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSRNOG00000012458 | ||||
| UniProt | UniProt_AC | P05182 | ||||
| Species | Rattus norvegicus | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog (32) | ||||||
| Structured_description | Automated_description | Enables Hsp70 protein binding activity and Hsp90 protein binding activity. Involved in several processes, including response to 3-methylcholanthrene; response to ethanol; and response to ozone. Located in Golgi membrane; endoplasmic reticulum membrane; and mitochondrial inner membrane. Used to study drug-induced hepatitis. Biomarker of several diseases, including alcohol use disorder; fatty liver disease (multiple); liver disease (multiple); middle cerebral artery infarction; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including acoustic neuroma; fatty liver disease; gastrointestinal system cancer (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human CYP2E1 (cytochrome P450 family 2 subfamily E member 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; (R)-carnitine. | Inferred_automatically | AGR_import |
