WormBase Tree Display for Gene: RGD:2471
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RGD:2471 | Identity | Name | CGC_name | Cyp2d2 | Inferred_automatically | AGR_import |
---|---|---|---|---|---|---|
Public_name | Cyp2d2 | |||||
DB_info | Database | RGD | id | 2471 | ||
AGR | cURI | RGD:2471 | ||||
EnsEMBL | ENSEMBL_geneID | ENSRNOG00000008988 | ||||
UniProt | UniProt_AC | P10634 | ||||
Species | Rattus norvegicus | |||||
Status | Live | |||||
Gene_info | Biotype | SO:0001217 | ||||
Ortholog (31) | ||||||
Structured_description | Automated_description | Enables monooxygenase activity. Involved in female pregnancy and response to xenobiotic stimulus. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; acute myeloid leukemia; asthma; autoimmune hepatitis; and rhinitis. Orthologous to human CYP2D6 (cytochrome P450 family 2 subfamily D member 6) and CYP2D7 (cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene)); PARTICIPATES IN phase I biotransformation pathway via cytochrome P450; INTERACTS WITH (+)-schisandrin B; 1,2-dichlorobenzene; 17beta-estradiol. | Inferred_automatically | AGR_import |