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WormBase Tree Display for Gene: RGD:2262

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Name Class

RGD:2262IdentityNameCGC_nameCamk2bInferred_automaticallyAGR_import
Public_nameCamk2b
DB_infoDatabaseRGDid2262
AGRcURIRGD:2262
EnsEMBLENSEMBL_geneIDENSRNOG00000052080
UniProtUniProt_ACP08413
SpeciesRattus norvegicus
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00006779Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionEnables calmodulin-dependent protein kinase activity; phospholipase binding activity; and protein kinase binding activity. A structural constituent of postsynaptic actin cytoskeleton. Involved in several processes, including cellular response to homocysteine; hippocampal neuron apoptotic process; and regulation of synapse organization. Acts upstream of or within long-term synaptic potentiation. Located in dendrite and perikaryon. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 54. Orthologous to human CAMK2B (calcium/calmodulin dependent protein kinase II beta); PARTICIPATES IN calcium/calmodulin dependent kinase 2 signaling pathway; p38 MAPK signaling pathway; type II interferon signaling pathway; INTERACTS WITH (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.Inferred_automaticallyAGR_import