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WormBase Tree Display for Gene: HGNC:9165

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Name Class

HGNC:9165IdentityNameCGC_nameSeptin4Inferred_automaticallyAGR_import
Other_name (26)
Public_nameSeptin4
DB_infoDatabaseHGNCid9165
AGRcURIHGNC:9165
EnsEMBLENSEMBL_geneIDENSG00000108387
UniProtUniProt_ACO43236
DOidDOID:12217
DOID:14330
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00006793Caenorhabditis elegansFrom_analysisInparanoid
OMA
OrthoInspector
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. [provided by RefSeq, Nov 2010]Inferred_automaticallyAGR_import