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WormBase Tree Display for Gene: HGNC:3388

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Name Class

HGNC:3388IdentityNameCGC_nameEpha4Inferred_automaticallyAGR_import
Other_name (11)
Public_nameEpha4
DB_infoDatabaseHGNCid3388
AGRcURIHGNC:3388
EnsEMBLENSEMBL_geneIDENSG00000116106
UniProtUniProt_ACP54764
DOidDOID:10652
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00006868Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]Inferred_automaticallyAGR_import