WormBase Tree Display for Gene: HGNC:30788
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| HGNC:30788 | Identity | Name | CGC_name | Tle6 | Inferred_automatically | AGR_import |
|---|---|---|---|---|---|---|
| Other_name | RGD:1343822 | |||||
| FLJ14009 | ||||||
| GRG6 | ||||||
| MGC14966 | ||||||
| OZEMA15 | ||||||
| PREMBL | ||||||
| transducin like enhancer of split 6 | ||||||
| transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila) | ||||||
| transducin-like enhancer protein 6 | ||||||
| Public_name | Tle6 | |||||
| DB_info | Database | HGNC | id | 30788 | ||
| AGR | cURI | HGNC:30788 | ||||
| EnsEMBL | ENSEMBL_geneID | ENSG00000104953 | ||||
| UniProt | UniProt_AC | Q9H808 | ||||
| OMIM | gene | 612399 | ||||
| DO | id | EFO:MONDO:0014769 | ||||
| Species | Homo sapiens | |||||
| Status | Live | |||||
| Gene_info | Biotype | SO:0001217 | ||||
| Ortholog | WBGene00006773 | Caenorhabditis elegans | From_analysis | EnsEMBL-Compara | ||
| OrthoFinder | ||||||
| Panther | ||||||
| Structured_description | Automated_description | This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] | Inferred_automatically | AGR_import |
