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WormBase Tree Display for Gene: HGNC:15460

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Name Class

HGNC:15460IdentityNameCGC_nameCacna2d3Inferred_automaticallyAGR_import
Other_nameRGD:1349571
HSA272268
alpha2delta-3
calcium channel alpha2-delta3 subunit
calcium channel, voltage-dependent, alpha 2/delta 3 subunit
calcium channel, voltage-dependent, alpha 2/delta subunit 3
voltage-dependent calcium channel subunit alpha-2/delta-3
voltage-gated calcium channel subunit alpha-2/delta-3
Public_nameCacna2d3
DB_infoDatabaseHGNCid15460
AGRcURIHGNC:15460
EnsEMBLENSEMBL_geneIDENSG00000157445
UniProtUniProt_ACQ8IZS8
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00006772Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import