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WormBase Tree Display for Gene: HGNC:1460

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Name Class

HGNC:1460IdentityNameCGC_nameCamk2aInferred_automaticallyAGR_import
Other_name (17)
Public_nameCamk2a
DB_infoDatabaseHGNCid1460
AGRcURIHGNC:1460
EnsEMBLENSEMBL_geneIDENSG00000070808
UniProtUniProt_ACQ9UQM7
OMIMgene114078
DOidDOID:10652
DOID:3070
DOID:0081224
DOID:0080228
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00006779Caenorhabditis elegansFrom_analysisHieranoid
Inparanoid
OMA
OrthoFinder
OrthoInspector
Panther
PhylomeDB
SonicParanoid
Structured_descriptionAutomated_descriptionThe product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2018]Inferred_automaticallyAGR_import