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WormBase Tree Display for Gene: HGNC:13829

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Name Class

HGNC:13829IdentityNameCGC_nameWnt10aInferred_automaticallyAGR_import
Other_nameRGD:1315958
ECTD16
FLJ14301
OODD
SSPS
STHAG4
protein Wnt-10a
wingless-type MMTV integration site family member 10A
wingless-type MMTV integration site family, member 10A
Public_nameWnt10a
DB_infoDatabaseHGNCid13829
AGRcURIHGNC:13829
EnsEMBLENSEMBL_geneIDENSG00000135925
UniProtUniProt_ACQ9GZT5
OMIMgene606268
DOidDOID:2121
DOID:0111647
DOID:0050591
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00003029Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
PhylomeDB
Structured_descriptionAutomated_descriptionThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import