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WormBase Tree Display for Gene: HGNC:12541

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Name Class

HGNC:12541IdentityNameCGC_nameUgt1a9Inferred_automaticallyAGR_import
Other_name (19)
Public_nameUgt1a9
DB_infoDatabaseHGNCid12541
AGRcURIHGNC:12541
EnsEMBLENSEMBL_geneIDENSG00000241119
UniProtUniProt_ACO60656
DOidDOID:4947
SpeciesHomo sapiens
StatusLive
Gene_infoBiotypeSO:0001217
OrthologWBGene00018206Caenorhabditis elegansFrom_analysisEnsEMBL-Compara
Hieranoid
Inparanoid
OMA
OrthoInspector
SonicParanoid
Structured_descriptionAutomated_descriptionThis gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008]Inferred_automaticallyAGR_import