WormBase Tree Display for GO_term: GO:0060070
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| GO:0060070 | Name | canonical Wnt signaling pathway | |
|---|---|---|---|
| Definition | A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. | ||
| Synonym | Exact | canonical Wnt receptor signaling pathway | |
| canonical Wnt-activated signaling pathway | |||
| Wnt receptor signaling pathway through beta-catenin | |||
| Wnt receptor signaling pathway via beta-catenin | |||
| Wnt receptor signalling pathway through beta-catenin | |||
| Narrow | frizzled-1 receptor signaling pathway | ||
| Status | Valid | ||
| Type | Biological_process | ||
| Child | Instance (15) | ||
| Component | GO:1904886 | ||
| GO:2000286 | |||
| Parent | Instance_of | GO:0016055 | |
| Attributes_of | Motif | INTERPRO:IPR015668 | |
| INTERPRO:IPR017049 | |||
| Index | Ancestor (14) | ||
| Descendant (22) | |||
| GO_annotation (40) | |||
| Version | Gene Ontology releases/2023-11-15 |
