WormBase Tree Display for GO_term: GO:0060070

GO:0060070 Name: canonical Wnt signaling pathway
  Definition: A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
  Synonym: Exact: canonical Wnt receptor signaling pathway
      canonical Wnt-activated signaling pathway
      Wnt receptor signaling pathway through beta-catenin
      Wnt receptor signaling pathway via beta-catenin
      Wnt receptor signalling pathway through beta-catenin
    Narrow: frizzled-1 receptor signaling pathway
  Status: Valid
  Type: Biological_process
  Child: Instance: GO:0044336
      GO:0044337
      GO:0044338
      GO:0061316
    Component: GO:1904886
      GO:2000286
  Parent: Instance_of: GO:0016055
  Attributes_of: Motif: INTERPRO:IPR015668
      INTERPRO:IPR017049
    Index: Ancestor (12)
      Descendant: GO:0044336
        GO:0044337
        GO:0044338
        GO:0061316
        GO:1904886
        GO:2000286
    GO_annotation (40)
  Version: Gene Ontology releases/2024-03-28