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WormBase Tree Display for GO_term: GO:0008219

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Name Class

GO:0008219Namecell death
DefinitionAny biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
SynonymRelatedaccidental cell death
necrosis
StatusValid
TypeBiological_process
ChildInstanceGO:0012501
ParentInstance_ofGO:0009987
Attributes_ofMotifINTERPRO:IPR015290
IndexAncestorGO:0008150
GO:0009987
Descendant (163)
VersionGene Ontology releases/2023-11-15