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WormBase Tree Display for GO_term: GO:0007094

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Name Class

GO:0007094Namemitotic spindle assembly checkpoint signaling
DefinitionA mitotic cell cycle checkpoint that delays mitotic sister chromatid separation and consequently the mitotic metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle. Spindle assembly checkpoint signaling begins with the activated Mph family kinase, and results in the inhibition of the Anaphase Promoting Complex and its activator Sleepy/Cdc20 by the mitotic checkpoint complex (MCC).
Alt_idGO:0044810
GO:0072480
GO:1902420
SynonymExactmitotic cell cycle spindle assembly checkpoint
mitotic checkpoint
mitotic spindle assembly checkpoint
mitotic spindle assembly checkpoint signalling
signal transduction involved in mitotic cell cycle spindle assembly checkpoint
signal transduction involved in mitotic spindle assembly checkpoint
NarrowDma1-dependent checkpoint
Mad2-dependent checkpoint
SAC-independent checkpoint
signal transduction involved in Dma1-dependent checkpoint
signal transduction involved in SAC-independent checkpoint
signaling cascade involved in Dma1-dependent checkpoint
signaling cascade involved in SAC-independent checkpoint
signalling cascade involved in Dma1-dependent checkpoint
signalling cascade involved in SAC-independent checkpoint
Relatedsignaling pathway involved in Dma1-dependent checkpoint
signaling pathway involved in SAC-independent checkpoint
signalling pathway involved in Dma1-dependent checkpoint
signalling pathway involved in SAC-independent checkpoint
StatusValid
TypeBiological_process
ParentInstance_ofGO:0045841
GO:0071173
GO:0071174
Attributes_ofMotifINTERPRO:IPR008672
INTERPRO:IPR015661
INTERPRO:IPR016242
INTERPRO:IPR026231
INTERPRO:IPR028593
INTERPRO:IPR039339
IndexAncestor (56)
GO_annotation (42)
VersionGene Ontology releases/2023-11-15