WormBase Tree Display for Expr_pattern: Expr9444
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| Expr9444 | Expression_of | Gene | WBGene00006412 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006412 | ||
| Expression_data | Anatomy_term (18) | ||
| GO_term | GO:0005886 | ||
| GO:0045202 | |||
| GO:0036194 | |||
| Subcellular_localization | Bright punctate staining was observed in dendritic (postsynaptic) regions. Clear punctate staining was also observed in presynaptic regions of each neuronal type. For example, in the DA9 motor neuron, bright NLG-1::YFP puncta were present in the ventral postsynaptic domain, and dimmer puncta were present in the dorsal presynaptic region. Puncta were excluded from the synapse-poor region between the cell body and dorsal presynaptic region and from the anterior asynaptic region of the dorsal process. To further study the punctate staining in the presynaptic region, NLG-1::YFP localization was examined in animals expressing the tagged synaptic vesicle protein mCherry::RAB-3 in DA9. In the dorsal axon, NLG-1::YFP puncta partially colocalized with puncta containing mCherry::RAB-3, suggesting that NLG-1::YFP localization is perisynaptic. | ||
| Sub-cellular localization within the body wall muscle: Muscle cell membrane +/- Muscle arms | |||
| Type | Reporter_gene | ||
| Pattern | nlg-1 is expressed in a subset of neurons in C. elegans adults, including ~20 cells in the ventral nerve cord and ~20 cells in the head. The nlg-1-expressing cells in the ventral nerve cord were identified as the cholinergic VA and DA motor neurons. Authors also identified the two AIY and two URB interneurons and the four URA motor neurons in the head, and the two PVD mechanosensory and two HSN motor neurons in the body, as nlg-1-expressing cells. Finally, faint Pnlg-1::YFP expression was also observed in body wall muscles. | ||
| Reference | WBPaper00038444 | ||
| Transgene | WBTransgene00014369 |
