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WormBase Tree Display for Expr_pattern: Expr9390

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Name Class

Expr9390Expression_ofGeneWBGene00003089
Reflects_endogenous_expression_ofWBGene00003089
Expression_dataLife_stageWBls:0000003
WBls:0000041
WBls:0000023
Anatomy_termWBbt:0003673Certain
WBbt:0003734Certain
WBbt:0005753Certain
WBbt:0008182Certain
GO_termGO:0005634
GO:0005737
GO:0097433
Subcellular_localizationSub-cellular localization within the body wall muscle: Dense bodies, Cytoplasm, +/- Nucleus
The LTD-1::GFP construct is expressed in the apical regions of the dorsal and ventral hypodermis in very tightly organized circumferential filament bundles. This cytoskeletal expression pattern mirrors the intracellular distribution of actin and tubulin in C. elegans. In late embryos, the GFP signal is localized to the apical junction between hyp 5, hyp 6 and hyp 7 and between the seam cells and the P blast cells in the ventral midline. This signal highlights the cell fusion processes that take place during post-embryonic development. The ltd-1 reporter is also expressed throughout the seam cell division process. It clearly outlines the cytokinesis between posterior mother cells and anterior daughter cells and illustrates the subsequent fusion of the anterior daughter cells to the hypodermal syncitium. The GFP signal is also observed in longitudinal filaments within the cytoplasm linking both extremities of the elongating seam cells and in the alae formed by their fusion.
TypeReporter_gene
PatternThe LTD-1::GFP signal is present throughout the development of C. elegans. This signal was detected as early as the 2-fold embryo. The ltd-1 reporter is also expressed throughout the seam cell division process. Its expression is observed in the seam cells of the early embryo and in the larval stages once these cells have commenced division. The LTD-1::GFP signal is also observed in rectal epithelial cells (tentatively, U and Y cells) and in the terminal bulb (marginal cells) and isthmus of the pharynx from hatching to adulthood.
ReferenceWBPaper00038444
TransgeneWBTransgene00014315