WormBase Tree Display for Expr_pattern: Expr8558
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| Expr8558 | Expression_data | Life_stage | WBls:0000005 |
|---|---|---|---|
| GO_term | GO:0005938 | ||
| Subcellular_localization | CABP11 (140 kDa) localizes to the actin-rich cortex of the one-cell embryo in a dramatic fashion. Between the time when the pronuclei meet and the end of metaphase of the first cell cycle (~10 min), CABP11 is enriched in the anterior cortex of one-cell embryos. This anterior enrichment occurs relative to cortical actin itself, which is no less abundant in the posterior than anterior. There is some variability in the size of the anterior cap and CABP11 is not completely excluded from the posterior. Two-cell embryos also show asymmetry in CABP11 localization. In the posterior cell, P1, CABP11 appears to be enriched in the anterior cortex. | ||
| Type | Antibody | ||
| Remark | New Symbol: CABP15. | ||
| Picture: Figure 6 | |||
| Since this is also the region where AB and P1 come together, authors cannot rule out the possibility that this is the posterior cortex of AB. None the less, two pieces of evidence suggest that the enrichment seen is in the anterior of P1 (i) by carefully following the actin cortical staining in each cell, we appear to be able to discriminate between AB's and P1's cortex at the cellcell boundary, and CABP11 is strongly present on P1's cortex; and (ii) CABP11 localizes to the bright dot of actin that is thought to reside on the anterior cortex of P1. The staining of CABP11 in the cortex of the anterior cell, AB, is more complex and apparently very dynamic. | |||
| Reference | WBPaper00002796 | ||
| Antibody_info | WBAntibody00001809 |
