WormBase Tree Display for Expr_pattern: Expr8299
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| Expr8299 | Expression_of | Gene | WBGene00004921 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004921 | |||
| Expression_data | Anatomy_term | WBbt:0003679 | Certain | |
| GO_term | GO:0045202 | |||
| Subcellular_localization | Distribution of SNT-1A is synaptic. | |||
| Type | Reporter_gene | [snt-1::SNT-1A::CFP; snt-1::SNT-1B::YFP]. SNT-1A::CFP and SNT-1B::YFP transgenes were integrated separately, and a strain containing both integrated transgenes was constructed. | ||
| Pattern | Imaging this strain revealed significant differences in SNT-1 isoform expression and localization. The SNT-1A isoform is abundantly expressed in most neurons, and the distribution of this isoform is synaptic, resembling that of the endogenous SNT-1 (see Expr334). In contrast, the SNT-1B isoform is expressed at lower levels and in fewer neurons than SNT-1A. Many neurons express both SNT-1A and -1B, although the relative amount of each isoform varies greatly between individual cells, and some neurons appear to express only the SNT-1A isoform. | |||
| Remark | Picture: Figure 3. | |||
| Reference | WBPaper00029143 | |||
| Transgene | WBTransgene00005418 |
