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WormBase Tree Display for Expr_pattern: Expr813

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Name Class

Expr813Expression_ofGeneWBGene00004719
Reflects_endogenous_expression_ofWBGene00004719
Expression_dataLife_stageWBls:0000024
WBls:0000003
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
Anatomy_termWBbt:0005735Certain
GO_termGO:0030424
Subcellular_localizationFluorescence appeared as a combination of punctate and diffuse staining within the axon.
TypeAntibodyAntibodies against a unique region of SAD-1.
PatternOnly weak expression of SAD-1 was visible in wild-type animals, but in animals overexpressing SAD-1 from the endogenous promoter SAD-1 immunoreactivity was present throughout the nervous system. As with psad-1GFP, expression was first seen in the late embryo. Observed no consistent anti-SAD-1 staining in sad-1(ky289) null animals,suggesting that the antibodies are specific for SAD-1 protein. The onset of sad-1 expression in the late embryo is consistent with a role for SAD-1 in synaptogenesis, as this is the time when many synapses are first made.
PictureWBPicture0000009603
ReferenceWBPaper00004523
Antibody_infoWBAntibody00000343