WormBase Tree Display for Expr_pattern: Expr7809
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| Expr7809 | Expression_of | Gene | WBGene00007010 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00007010 | |||
| Expression_data | Anatomy_term | WBbt:0004017 | Certain | |
| GO_term | GO:0005737 | |||
| GO:0016324 | ||||
| Subcellular_localization | The GFP-ALX-1 fusion protein appeared punctate in most tissues. In the intestine, GFP-ALX-1 was enriched near the apical plasma membrane (PM) and was also clearly enriched on distinct cytoplasmic puncta. | |||
| Type | Reporter_gene | |||
| Pattern | Ubiquitous expression of GFP-ALX-1 was observed with notably high levels of expression in the intestine, hypodermis, body-wall muscles, nervous system, spermatheca, coelomocytes, and pharynx. | |||
| Picture | WBPicture0000009865 | |||
| Remark | Intestine-specific expression of equivalent fusions of ALX-1 to GFP or mCherry produced indistinguishable subcellular localization patterns and rescued alx-1 mutant phenotypes, indicating that the expression pattern and subcellular localization of the reporters very likely reflect those of the endogenous protein. | |||
| Picture: Figure 2. | ||||
| Reference | WBPaper00031193 | |||
| Transgene | WBTransgene00001780 |
