WormBase Tree Display for Expr_pattern: Expr58
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| Expr58 | Expression_of | Gene | WBGene00003182 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00003182 | |||
| Clone | F27D1 | |||
| Expression_data | Life_stage | WBls:0000024 | ||
| WBls:0000038 | ||||
| WBls:0000027 | ||||
| WBls:0000035 | ||||
| WBls:0000041 | ||||
| WBls:0000018 | ||||
| WBls:0000019 | ||||
| WBls:0000020 | ||||
| WBls:0000021 | ||||
| Anatomy_term | WBbt:0003675 | Certain | ||
| WBbt:0003679 | Partial | |||
| WBbt:0005733 | Partial | |||
| Type | Antibody | to MEF2 | ||
| Reporter_gene | ||||
| Pattern | Antibody staining: No worm Ab available. Two D.m. Ab fail to stain anything in the worm that looks real. | |||
| lacZ reporter gene expression: Multiple constructs with multiple lines. Expression begins late in embryogenesis at about 11/2 fold stage in a few cells in the head (neuronal precursors?). Then strong expression by 3-fold stage in most tissue including neurons, all muscle, hypodermis. Not in gut. Expression continues in all tissues (except gut) into adulthood. | ||||
| Remark | MADS box transcription factor related to SRF factors. In vertebrates, MEF2 is involved in the activation of muscle specific genes. It is also expressed in neuronal tissue but its role there is unstudied. Vertebrate Homologs: Human and mouse protein(s) MEF2a, MEF2b, MEF2c, MEF2d. Invertebrate Homologs: Drosophila protein D-MEF2 | |||
| MEF2-gene deleted by mnDf111 on I. | ||||
| late embryo(author) = fully-elongated embryo(curator). | ||||
| no expression in gut | ||||
| Reference | WBPaper00004244 | |||
| Transgene | WBTransgene00029644 | |||
| Antibody_info | WBAntibody00001839 |
