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WormBase Tree Display for Expr_pattern: Expr4956

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Name Class

Expr4956Expression_ofGeneWBGene00003516
Reflects_endogenous_expression_ofWBGene00003516
Expression_dataLife_stageWBls:0000024
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
WBls:0000019
WBls:0000020
WBls:0000021
Anatomy_termWBbt:0003679Partial
WBbt:0004506Certain
WBbt:0004520Certain
WBbt:0005733Certain
WBbt:0005775Certain
WBbt:0005829Certain
WBbt:0006748Certain
WBbt:0006749Certain
WBbt:0006750Certain
GO_termGO:0048786
Subcellular_localizationNAB-1::GFP puncta partially co-localized with the synaptic-vesicle protein SNT-1 and the active-zone protein UNC-10, suggesting that NAB-1 is present in presynaptic regions that are associated with vesicle pools and active zones. Similar to NAB-1, SAD-1 also showed co-localization with SNT-1. NAB-1::GFP and SAD-1 also showed partial co-localization, where each NAB-1::GFP punctum was associated with SAD-1 staining.
TypeReporter_gene
PatternNAB-1::GFP expression is restricted to epithelia and neurons. The earliest expression was observed in the hypodermis of 2-fold-stage early embryos. Immediately prior to hatching, this expression became restricted to the epithelial excretory canal and the nervous system, including the central nervous system and the motoneurons (dorsal and ventral nerve cords. In L3 and L4 larvae, NAB-1::GFP also localized transiently at the membranes of the developing vulva epithelia. Also expressed in distal tip cell (pers. comm. from Wesley Hung 11-17-07.)
PictureWBPicture0000007735
RemarkPicture: Fig. 5, Fig 6.
ReferenceWBPaper00028874
TransgeneWBTransgene00000610