Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Expr_pattern: Expr4493

expand all nodes | collapse all nodes | view schema

Name Class

Expr4493Expression_ofGeneWBGene00000424
Reflects_endogenous_expression_ofWBGene00000424
Expression_dataLife_stageWBls:0000024
WBls:0000038
WBls:0000027
WBls:0000035
WBls:0000041
WBls:0000015
WBls:0000021
WBls:0000010
WBls:0000013
Anatomy_termWBbt:0004017Certain
GO_termGO:0009898
GO:0031410
Subcellular_localizationAt the subcellular level, the signal was absent in the nucleus, easily identified as a circular void within the cell. The distribution of the marker in cytosol sometimes assumed a vesicular structure. The intracellular vesicles in the scanned images overlapped with most, if not all, the granules observed by differential interference contrast microscopy. The marker accumulated at the boundaries between neighboring cells, appearing much more sparsely at cell surfaces facing the egg shell where no neighboring cell was present, and little accumulation was seen at the boundary facing the germ line cells Z2 and Z3. Large round vesicular structures exhibiting the strongest signals correspond to the cells undergoing apoptosis, indicating the cell boundaries between cells undergoing programmed cell death and the cells engulfing the dying cells.
TypeReporter_gene
PatternThe embryos near the vulva assumed stronger fluorescence of the CED-10::GFP::CED-10 marker than their younger, more distant siblings. The signal was not detectable until the 50-cell stage of the gastrulating embryo, when the marker started to accumulate beneath the cell boundaries. The signal gradually strengthened until the 3-fold stage, and remained unchanged thereafter until adulthood. The marker was expressed ubiquitously in all cells except the germ line Z2 and Z3 cells.
ReferenceWBPaper00029000
TransgeneWBTransgene00004968