WormBase Tree Display for Expr_pattern: Expr3920
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| Expr3920 | Expression_of | Gene | WBGene00001132 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00001132 | |||
| Expression_data | Life_stage | WBls:0000024 | ||
| WBls:0000038 | ||||
| WBls:0000027 | ||||
| WBls:0000035 | ||||
| WBls:0000041 | ||||
| WBls:0000015 | ||||
| WBls:0000021 | ||||
| Anatomy_term | WBbt:0003673 | Certain | ||
| WBbt:0005451 | Certain | |||
| WBbt:0005733 | Certain | |||
| WBbt:0005813 | Certain | |||
| GO_term | GO:0005634 | |||
| GO:0005911 | ||||
| Subcellular_localization | Expressed in the cell-cell junctions of the embryonic hypodermis and in the hypodermal cell nuclei. | |||
| Type | Reporter_gene | |||
| Pattern | The ALP-1BCD/Enigma proteins are first detected during embryogenesis at the comma-stage in the cell-cell junctions of the embryonic hypodermis and in the hypodermal cell nuclei. At this stage, proteins begin to localize to circumferential fibers, similar to ALP-1A. At a later stage (fourfold), these circumferential bundles are more apparent, as is the late appearance of the ALP-1BCD/Enigma::GFPs in the developing body wall muscle. In a deeper optical section of the same embryo, it is evident that the ALP-1BCD/Enigma::GFP fusion proteins localize to cell-cell junctions in the developing pharynx. At this stage, the pharynx is still developing, and the arcade cells that are required to attach the anterior part of the pharynx to the mouth have not yet become epithelialized. Once the pharynx begins to differentiate, an enrichment of the ALP-1BCD/Enigma::GFPs was seen in the pharyngeal muscles and in specialized pharyngeal epithelial cells called marginal cells. This pharyngeal expression persists throughout development and is most prevalent in adults. | |||
| Reference | WBPaper00026945 | |||
| Transgene | WBTransgene00001779 |
