WormBase Tree Display for Expr_pattern: Expr3658
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| Expr3658 | Expression_of | Gene | WBGene00006655 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006655 | ||
| Expression_data | Anatomy_term (25) | ||
| GO_term | GO:0005634 | ||
| GO:0005737 | |||
| GO:0043005 | |||
| Subcellular_localization | Several of these neurons have processes leading to the tip of the head or tail. The GFP fluorescence was also observed in form of small aggregates (0.3 um to 0.9 um) along the neuronal processes. TUB-1::GFP is localized mostly to the cytoplasm with very little signal in the nucleus. This is in contrast to results from mammalian cell culture where tubby is primarily found in the nucleus. The cytoplasmic localization suggests that either C. elegans TUB-1 only transiently functions in the nucleus or a very small proportion in the nucleus is sufficient for the function or it is required only in the cytoplasm. | ||
| Type | Reporter_gene | ||
| Pattern | GFP expression was found in several neurons, including the ciliated amphid neurons (ASI, ADL, ASK, AWB, ASH, ASJ) in the head region and ciliated phasmid neurons (PHA and PHB) in the tail, as judged by colocalization of GFP with DiI as well as in PDE and several labial neurons in the head. Expression in neurons was visible early in developing young larvae enclosed in the egg. | ||
| Picture | WBPicture0000011862 | ||
| Reference | WBPaper00026699 | ||
| Transgene | WBTransgene00028795 |
