WormBase Tree Display for Expr_pattern: Expr3116
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| Expr3116 | Expression_of | Gene | WBGene00002229 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00002229 | |||
| Expression_data | Life_stage | WBls:0000003 | ||
| WBls:0000041 | ||||
| Anatomy_term | WBbt:0005784 | Certain | ||
| GO_term | GO:0005819 | |||
| GO:0005694 | ||||
| GO:0005654 | ||||
| Subcellular_localization | In the gonad, staining was bright in germline nuclei of the distal mitotic zone, dim in early meiotic prophase nuclei, and then bright again in late prophase nucleoplasm. Just before fertilization, KLP-19 concentrated on prophase chromosomes. During metaphase of meiosis I, staining concentrated slightly in the body of the spindle, more around the periphery of chromosomes, and most between homologous chromosomes. A similar pattern was seen in meiosis II. In embryos, during most of mitotic prophase, KLP-19 concentrated in nucleoplasm. In prometaphase, it concentrated slightly in the body of the spindle and more strongly around the periphery of chromosomes. In anaphase, it left chromosomes and concentrated in the spindle interzone. These dynamic patterns predict that KLP-19 functions in meiotic and mitotic spindles and suggest that, despite the lack of a recognizable DNA-binding motif, it can associate with chromosomes during prometaphase congression. | |||
| Type | Antibody | |||
| Pattern | Strong antibody staining was seen primarily in areas with dividing cells; i.e., the gonad and embryos. | |||
| Picture | WBPicture0000008968 | |||
| WBPicture0000008969 | ||||
| Reference | WBPaper00024405 | |||
| Antibody_info | WBAntibody00000778 |
