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WormBase Tree Display for Expr_pattern: Expr3038

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Name Class

Expr3038Expression_ofGeneWBGene00008549
Reflects_endogenous_expression_ofWBGene00008549
Expression_dataLife_stage (11)
Anatomy_termWBbt:0003679Partial
WBbt:0003681Certain
WBbt:0004506Certain
WBbt:0004520Certain
WBbt:0005175Certain
WBbt:0005733Certain
WBbt:0005772Certain
WBbt:0005813Certain
WBbt:0007809Certain
GO_termGO:0005634
Subcellular_localizationExpressed in nuclei.
TypeReporter_gene
PatternFor din-1L, 8 kb of the din-1 upstream region was placed before gfp followed by din-1LB cDNA. Extrachromosomal arrays dhEx191 and dhEx194 were expressed in the nuclei of most cells from embryo to adult, as well as in dauer larvae. din-1L expressed more strongly in embryo and L1 larvae than din-1S, consistent with an earlier role.
din-1S::gfp localized to the nuclei of most cell types. Detected in hypodermis, seam, intestine, and somatic gonad including the distal tip cells, din-1S was also expressed in neurons, vulval precursors, body wall muscle, and pharynx, all tissues with heterochronic phenotypes or remodeled during dauer. Expression was first detected in a few nuclei by the comma stage of embryogenesis. By hatch, din-1S was widely expressed, albeit weakly. Overall expression in most tissues was detected at various levels into adult and in dauer larvae. Interestingly, in late L1 and L2 larvae din-1S was often (75%, n = 16) highly expressed in the XXX cells, specialized neuroendocrine cells proposed to be a site of synthesis for the daf-9-produced hormone.
PictureWBPicture0000008472
ReferenceWBPaper00024451
TransgeneWBTransgene00028312