WormBase Tree Display for Expr_pattern: Expr2830
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| Expr2830 | Expression_of | Gene | WBGene00003000 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00003000 | ||
| Expression_data | Life_stage | WBls:0000024 | |
| WBls:0000038 | |||
| WBls:0000027 | |||
| WBls:0000035 | |||
| WBls:0000041 | |||
| WBls:0000015 | |||
| WBls:0000021 | |||
| WBls:0000013 | |||
| Anatomy_term (38) | |||
| GO_term | GO:0005634 | ||
| Subcellular_localization | Expressed in nuclei of multiple neurons in the head and lumbar ganglia. | ||
| Type | Reporter_gene | ||
| Pattern | Expression of lin-11::GFP is first observed after the time when most postmitotic neurons are born (at approx. 300 minutes postfertilization). In larvae, the LIN-11::GFP fusion protein is localized to the nuclei of multiple neurons in the head and lumbar ganglia. In addition, lin-11 expression is observed in uterine and vulval cells, as well as in the VC motor neurons. | ||
| In the lumbar ganglia, lin-11 expression is observed in the PVPL/R and PVQ neurons, and in an additional unpaired neuron identified as DVC or DVA. In contrast to shorter lin-11::GFP fusion genes, the rescuing lin-11::GFP fusion gene is not expressed in the PHA sensory neurons. In the head, lin-11 expression was observed in the sensory neurons ADF and ADL, in the interneurons AIZ, RIC and AVG, and in another neuron type tentatively identified as either AVH or AVJ. However, expression in a number of additional neurons was also observed using the full-length lin-11::GFP fusion gene. lin-11 expression was observed in the AVA and AVE interneurons. Faint and occasional expression was also detected in the ASH polymodal sensory neurons. | |||
| lin-11 expression was observed in the AWA neurons in embryos and young larvae, but not in later stages. Expression of lin-11 in the AWA neurons is observed consistently in three-fold embryos, where expression of lin-11 overlaps with that of ODR-7 (32/32 AWA neurons examined). Expression decreases by hatching such that in L1 larvae, expression in the AWA neurons is fainter and observed only occasionally, and is absent in later larvae and adults. lin-11 expression was also observed strongly and consistently in the ASG chemosensory neurons. Expression in the ASG neurons is observed throughout postembryonic development. lin-11 expression was also detected in a few other non-sensory neurons in the head and tail that were not identified definitively. | |||
| Picture | WBPicture0000007457 | ||
| WBPicture0000007458 | |||
| Reference | WBPaper00004906 | ||
| Transgene | WBTransgene00000296 |
