WormBase Tree Display for Expr_pattern: Expr2346
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Expr2346 | Expression_of | Gene | WBGene00000871 | ||
---|---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00000871 | ||||
Homol | Homol_homol | C37A2:Expr | |||
Expression_data | Life_stage (9) | ||||
Anatomy_term | WBbt:0004017 | Partial | |||
Remark | Expressed in all somatic cells under division. | ||||
Type | Reporter_gene | ||||
Pattern | Expression was first detected during early embryogenesis(28-cell stage) and continued in all proliferating cells of the embryo. Once on, the GFP reporter showed no fluctuation in levels during the embryonic cell cycle and was continuous until proliferation of the lineage was complete. Expression postembryonically was detected in all proliferating somatic cell lineages of the hermaphrodite throughout development and remained constant while the lineage was proliferating. Expression was specifically assayed in the P and seam cell lineages, several neurons outside the ventral nerve cord, vulval precursor cells (VPCs), intestinal cells, and the somatic gonad. Reporter gene expression was usually lost once cell divisions were complete, although persistent expression was often seen in seam cells, intestinal cells, and scattered neurons. Germline expression of the cye-1::GFP reporter gene was not observed, presumably reflecting germline silencing of the simple, extrachromosomal arrays generated in these experiments. Because the germline and early embryos are CYE-1 antibody-positive, authors have attempted to visualize germline CYE-1::GFP fusion proteins by using complex arrays and germline promoters, but all attempts have been unsuccessful. | ||||
Reference | WBPaper00005708 | ||||
Transgene | WBTransgene00028013 |