WormBase Tree Display for Expr_pattern: Expr1904
expand all nodes | collapse all nodes | view schema
| Expr1904 | Expression_of | Gene | WBGene00004951 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004951 | |||
| Expression_data | Life_stage | WBls:0000003 | ||
| Anatomy_term | WBbt:0003681 | Certain | ||
| WBbt:0005733 | Certain | |||
| WBbt:0005735 | Certain | |||
| WBbt:0005772 | Certain | |||
| WBbt:0005813 | Certain | |||
| GO_term | GO:0016020 | |||
| Subcellular_localization | membrane | |||
| Type | Antibody | Rabbit polyclonal antiserum against spc-1, designated as AS1. | ||
| Pattern | Wild-type embryos were stained with AS1 and examined by immunofluorescence microscopy. In early embryos, alpha-spectrin is found at or near the cell membrane in most if not all cells starting at the earliest stage of embryogenesis, indicating that alpha-spectrin is maternally supplied. After morphogenesis and organogenesis initiates, alpha-spectrin localizes to the body wall muscle, hypodermis, pharynx, intestine, and developing nervous system. In epithelial tissues, alpha-spectrin is found at both the apical and basolateral regions of the membrane. This is unlike the localization pattern observed for beta-spectrin, which is found in only the basolateral region of the membrane. With the exception of the apical regions, the localization of alpha-spectrin overlaps with the distribution of beta-spectrin. | |||
| Picture | WBPicture0000008955 | |||
| Remark | No details on expression pattern at other stages. | |||
| spc-1 = alpha-spectrin | ||||
| Reference | WBPaper00005321 | |||
| Antibody_info | WBAntibody00000528 |
