WormBase Tree Display for Expr_pattern: Expr1650
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| Expr1650 | Expression_of | Gene | WBGene00004732 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00004732 | |||
| Expression_data | Life_stage | WBls:0000003 | ||
| Anatomy_term | WBbt:0003679 | Certain | ||
| WBbt:0003681 | Certain | |||
| WBbt:0005733 | Certain | |||
| WBbt:0005735 | Certain | |||
| WBbt:0005784 | Certain | |||
| WBbt:0005813 | Certain | |||
| WBbt:0005829 | Certain | |||
| WBbt:0006749 | Certain | |||
| GO_term | GO:0005913 | |||
| Subcellular_localization | LAD-1 is localized to the plasma membrane of the cell bodies and axonal and dendritic processes. LAD-1 was strikingly localized to the plasma membrane at sites of cellcell contact as early as just before the two-cell stage. Localized LAD-1 was not detected in one-cell embryos, which lack sites of cellular contact. | |||
| Type | Antibody | Immunoblots of mixed stage worm lysates with an affinity purified antibody generated against the LAD-1 cytoplasmic tail. | ||
| Pattern | LAD-1 visualized by immunofluorescence was expressed in all cells throughout development, starting at the onset of embryogenesis with its expression increasing dramatically during embryonic morphogenesis. LAD-1 was highly expressed in the nervous system. LAD-1 is localized to the plasma membrane of the cell bodies and axonal and dendritic processes and in nonneuronal tissues such as the pharynx, hypodermis, body wall muscles, and the germline. Localized LAD-1 was not detected in one-cell embryos, which lack sites of cellular contact. | |||
| Picture | WBPicture0000008947 | |||
| Remark | No detailed description on postembryonic cellular localization. | |||
| Reference | WBPaper00004840 | |||
| Antibody_info | WBAntibody00000401 |
