WormBase Tree Display for Expr_pattern: Expr1615
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| Expr1615 | Expression_of | Gene | WBGene00006748 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00006748 | ||
| Expression_data | Life_stage | WBls:0000022 | |
| WBls:0000020 | |||
| WBls:0000021 | |||
| Anatomy_term (21) | |||
| Type | Reporter_gene | pR13A14lacZ expression pattern were also characterized in a strain in which the reporter construct was stably integrated into the genome (ZB167), which gave results consistent with those observed for mosaic animals. An identical expression profile was observed when a second fusion, including 2.5 kb upstream of the predicted initiation codon, was assayed. | |
| Pattern | pR13A14lacZ activity is apparent in the embryo and is first detected during the 3-fold stage, about 300 min prior to hatching. This staining is likely to occur in the embryonically derived DA, DB, and/or DD motor neurons. Beta-galactosidase activity is observed in additional neurons later in development and peaks during the L2 stage when intense staining of sensory neurons, interneurons in the nerve ring, and motor neurons in the ventral nerve cord are apparent. Strong staining persists into adulthood. Among the neurons that express pR13A14lacZ are the ASH and FLP sensory neurons, the PVM touch neuron, the PVC, AVB, AVA, and AVD command interneurons, and the PDA, PDB, DA, DB, DD, VA, VB, and VD classes of motor neurons. Additional neurons situated either within or in the vicinity of the nerve ring express the R13A1_4 reporter gene. In summary, R13A1_4 expression is neuron specific and restricted to about 45 cells. | ||
| Picture | WBPicture0000009578 | ||
| Remark | Reporter gene fusion type not specified. | ||
| Reference | WBPaper00002646 | ||
| Transgene | WBTransgene00000187 |
