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WormBase Tree Display for Expr_pattern: Expr16145

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Name Class

Expr16145Expression_ofGeneWBGene00006778
Reflects_endogenous_expression_ofWBGene00006778
Expression_dataAnatomy_term (46)
TypeGenome_editing
Reporter_gene
PatternWe found that in the adult nervous system unc-42 is strongly and consistently expressed in 40 neurons located in the head of the worm that fall into 15 anatomically distinct neuron classes. At the first larval stage, expression is detected in the same set of neuron classes as observed in the adult, with the addition of very weak and inconsistent expression in AVJ and SIA that disappears by the adult stage. In the embryo, expression is first observed in a few neuroblasts before the bean stage. At the bean stage, when most neurons have terminally divided, unc-42 expression commences and reaches the full complement of unc-42(+) cells at the 1.5-fold stage. The cellular sites of expression in the embryonic nervous system appear to be the same as observed post-embryonically, a notion further supported by recent scRNA data (Packer et al., 2019). No expression is observed outside the nervous system.
ReferenceWBPaper00061549
VariationWBVar02157632