WormBase Tree Display for Expr_pattern: Expr14917

Expr14917 Expression_of: Gene: WBGene00010755
    Reflects_endogenous_expression_of: WBGene00010755
  Expression_data: Life_stage: WBls:0000032 Anatomy_term: WBbt:0005733
    Anatomy_term: WBbt:0005733 Certain
        Life_stage: WBls:0000032
    Not_in_Anatomy_term: WBbt:0003987 Life_stage: WBls:0000032
      WBbt:0003989 Life_stage: WBls:0000032
  Subcellular_localization: vglu-2::gfp is exclusively expressed in a single interneuron class, AIA, where it localizes to vesicular structures in the soma, but not along the axon. In syncytial epidermis and in uterine tissue vglu-2::gfp most prominently localizes to early endosomes, and to a lesser degree apical clathrin-coated pits, TGN, and late endosomes.
  Type: Genome_editing
    Reporter_gene
  Pattern: While the expression of VGLU-2::GFP is similar during larval and adult stages inwell fed animals, the expression and localization pattern of VGLU-2::GFP is alteredsubstantially in dauer stage animals. Expression from the AIA neurons disappears and in the epidermis, the localization of VGLU-2::GFP appears much weaker and more diffuse. Upon recovery from the dauer stage, VGLU-2::GFP expression andlocalization resumes to the state observed in animals that have not gone through the dauer stage. Starvation alone does not affect VGLU-2::GFP expression and localization.
  Reference: WBPaper00058928
  Variation: WBVar02152776