WormBase Tree Display for Expr_pattern: Expr1317
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| Expr1317 | Expression_of | Gene | WBGene00002988 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00002988 | ||
| Expression_data | Life_stage | WBls:0000022 | |
| WBls:0000015 | |||
| WBls:0000021 | |||
| WBls:0000013 | |||
| Anatomy_term (15) | |||
| Type | Reporter_gene | ||
| Pattern | The expression of lim-6 in all neurons continues throughout adulthood. The expression of lim-6 in the uterus is dynamic. lim-6 reporter gene constructs (lim-6prom::GFP, lim-6up::GFP, lim-6r::GFP) start to be expressed in two uterine cells during the late L3/early L4 stage and the expression widens during the L4 stage to include the uv2 and uv3 cells, several uterine toroid (ut) cells, which form the lumen of the uterus and at least one cell type (sujn) of the spermatheca-uterine junction. Occasionally, weaker and less consistent expression can be observed in some cells of the distal side of the spermatheca, which connect the spermatheca to the rest of the somatic gonad. | ||
| The lim-6r::GFP fusion gene reveals expression in restricted set of neurons, epithelial cells of the uterus and the excretory system. Reporter gene expression in the nervous system begins late in embryogenesis at about 300 minutes of development, which is after these neurons have been generated and while they initiate neurite outgrowth. After hatching, lim-6r::GFP is expressed in one chemosensory neuron, ASEL, and in eight inter- and motorneurons. Most of these neurons are GABAergic, namely RMEL/R, AVL, RIS and DVB. RMEL/R, AVL and DVB are motorneurons, whereas RIS is an interneuron. The other three neurons, PVT and RIGL/R, express the neuropeptide FMRFamide. | |||
| Picture | WBPicture0000008012 | ||
| Remark | Reporter gene fusion type not specified. | ||
| Reference | WBPaper00003509 | ||
| Transgene | WBTransgene00027459 |
