WormBase Tree Display for Expr_pattern: Expr13138
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| Expr13138 | Expression_of | Gene | WBGene00013082 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00013082 | |||
| Expression_data | Anatomy_term | WBbt:0005759 | Certain | |
| GO_term | GO:0036064 | |||
| Subcellular_localization | GRDN-1a::GFP was broadly expressed during embryogenesis and was enriched at the presumptive nose starting at mid-embryogenesis, coinciding with the time period of sensory neuron differentiation and ciliogenesis (Sulston et al., 1983).The subcellular localization of GRDN-1a::GFP was reminiscent of that previously reported for BB and TZ proteins in embryonic head sensory neurons (e.g., Dammermann et al., 2009). Consistent with this notion, GRDN-1a::GFP was present at the AWB cilia base in larvae, and co-localized with the BB markers DYF-19 and GASR-8 in the PHA/PHB ciliated tail neurons in L1 larvae and adult AWB neurons, respectively. Intriguingly, GRDN-1a::GFP appeared to be enriched at the proximal ends of centrioles, and was completely excluded from the TZ marked by MKS-5::tagRFP. Together, these observations suggest that Girdin is localized to the BBs in C. elegans sensory neurons. | |||
| Picture | WBPicture0000014409 | |||
| Reference | WBPaper00050122 |
