WormBase Tree Display for Expr_pattern: Expr11487

Expr11487 Expression_of: Gene: WBGene00000995
    Reflects_endogenous_expression_of: WBGene00000995
  Expression_data: Anatomy_term: WBbt:0003679 Certain
      WBbt:0003903 Certain
      WBbt:0003904 Certain
      WBbt:0005733 Certain
      WBbt:0005833 Certain
      WBbt:0007028 Certain
  Type: Reporter_gene
  Pattern: The die-1 fosmid reporter is initially expressed very broadly throughout the developing embryo, including the hypodermis, where die-1 acts to ensure ventral enclosure during gastrulation. Mirroring antibody staining, reporter expression of the fosmid reporter vanishes at approximately 460 min of embryonic development. die-1 expression then reinitiates in many neurons,including both ASEL and ASER; shortly thereafter, expression in ASER becomes undetectable. ASEL-restricted expression is maintained throughout the embryonic, larval, and adult stages. die-1 is also expressed in an asymmetric manner in the AWC olfactory neuron pair. Most adult animals show a strong bias of expression of die-1 to either the left or right AWC neuron. This antisymmetric die-1 expression is already evident in late embryos when the initial decision of AWC asymmetry control is made. ASEL-specific expression of die-1can be observed before any AWC expression of die-1 is observed. Expression of the die-1 fosmid reporter correlates with the AWC OFF state.
  Remark: Temporal description
  Reference: WBPaper00044621
  Transgene: WBTransgene00008534