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WormBase Tree Display for Expr_pattern: Expr1146

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Name Class

Expr1146Expression_ofGeneWBGene00000289
Reflects_endogenous_expression_ofWBGene00000289
Expression_dataLife_stageWBls:0000023
WBls:0000015
WBls:0000021
WBls:0000010
WBls:0000013
Anatomy_term (37)
GO_termGO:0005886
GO:0030425
GO:0030424
Subcellular_localizationIn non-neuronal cells, much of the protein appears to associate with the plasma membrane. In neurons, CAM-1GFP is detected predominantly in axons and dendrites.
TypeReporter_gene[cam-1::gfp]. A functional cam-1gfp transgene that rescues the defects of cam-1 mutants.
PatternCAM-1GFP expression appears at the 200-cell stage in most cells of the embryo. Migrating ALM, BDU, CAN, HSN and ccM cells, which migrate embryonically and require cam-1 function for their migration, are likely to express CAM-1GFP, as most cells of the embryo express the transgene while these cells migrate. During the first larval stage, V cells often express CAM-1GFP at the time that they divide, and the Q-neuroblast descendents, which also require cam-1 function for their migration, express CAM-1GFP. During larval development, CAM-1GFP is highly expressed in the nervous system, as well as in intestinal, hypodermal and body-wall muscle cells and in parts of the pharynx.
RemarkReporter gene fusion type not specified.
ReferenceWBPaper00003653
TransgeneWBTransgene00007427